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. 2017 Nov 20;7:15873. doi: 10.1038/s41598-017-16221-8

Table 4.

Mean sequence composition of successful and unsuccessful Pfam protein sets, F = −2.

Amino acid Viral proteinsa All proteins Amino acid 2-mer Viral proteinsa All proteins
most successful least successful P-valueb most successful least successful P-valueb
E 6.6c 8.2c 6.8c 0.01 DE 8.3d 7.7d 4.1d 0.00
F 3.4 3.6 4.4 0.02 EE 4.2 7.5 4.1 0.02
H 2.0 1.7 2.1 0.15 EK 2.7 10.1 4.8 0.00
K 6.4 7.0 5.9 0.11 SN 5.4 4.6 1.6 0.00
N 5.5 4.5 3.9 0.17 SE 7.0 7.7 4.5 0.01
Q 4.2 4.2 3.7 0.16 RD 3.5 1.1 3.3 0.02
T 6.2 4.8 5.8 0.05 FA 1.9 1.6 4.0 0.02
W 0.9 0.9 1.5 0.01 FG 1.0 1.3 3.5 0.03
Y 2.5 2.7 3.6 0.01 YR 0.0 0.4 3.1 0.03
G 4.0 5.8 6.8 0.06 YV 0.7 1.1 3.1 0.03

aThe 20 most successful out of 44. bSignificance of the successful/unsuccessful differences. cAmino acid frequencies (%) for the types that differ most between successful/unsuccessful protein sets (10 smallest P-values). d2-mer frequencies (‰) for those that differ most between successful/unsuccessful protein sets (10 smallest P-values).