Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 20;7:15856. doi: 10.1038/s41598-017-15977-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Percentage shares of Sox2 and Sox9 expression in aCP and pCP. Sox2 expressing cells could be detected in only 7.8% of aCP and in 39.1% of the respective surrounding gliotic layer (a). In the latter Sox2+ cells appeared especially surrounding finger-like tumour protrusions (a). pCP specimen appeared always negative (b). Sox9 could be found in all tumour samples with showing a significantly stronger staining pattern in the core of aCP (c) compared to pCP (d) (p < 0.0001). This was also true for the gliotic layer where 98.4% of aCP and 66.7% of pCP showed Sox9+ cells. Nuclear β-catenin accumulating cell clusters (green: β-cat_nc), exclusively found in aCP always remained negative both for Sox2 and for Sox9.