Table 1.
Main characteristics of the ilSIRENTE and inCHIANTI populations.
| Characteristic | ilSIRENTE (n = 286) | inCHIANTI (n = 1055) |
|---|---|---|
| Age, years | 86.1 ± 4.9 | 67.8 ± 15.7 |
| Female | 170 (64) | 615 (58) |
| Education, years | 5.0 ± 1.6 | 8 ± 1.6 |
| Number of diseases | 1.9 ± 1.3 | 1.1 ± 0.8 |
| Specific diseases | ||
| Hypertension | 206 (72) | 484 (46) |
| Ischemic heart disease | 34 (12) | 89 (8) |
| Congestive heart failure | 18 (6) | 32 (3) |
| Cancer | 14 (5) | 57 (5) |
| Chronic obstructive pulmonary disease | 37 (13) | 65 (6) |
| Diabetes | 83 (29) | 127 (12) |
| Cerebrovascular diseases | 15 (5) | 35 (3) |
| Osteoarthritis | 53 (18) | 188 (18) |
| Number of medications | 3.3 ± 2.3 | 2.0 ± 1.3 |
| BMI, kg/m 2 | 25.3 ± 4.4 | 27.2 ± 4.1 |
| Physical performance measures | ||
| Short Physical Performance Battery summary score | 6.6 ± 3.9 | 10.2 ± 3.1 |
| 4-m walking speed (m/s) | 0.48 ± 0.31 | 1.04 ± 0.28 |
| Handgrip strength (kg) | 28.9 ± 14.6 | 30.7 ± 14.1 |
| Functional status measures | ||
| ADL score | 1.5 ± 2.5 | 0.25 ± 1.0 |
| IADL score | 3.1 ± 2.5 | 0.86 ± 2.1 |
| CPS score | 0.9 ± 1.5 | — |
| MMSE score | — | 26.2 ± 2.8 |
| Hematological parameters | ||
| Albumin, g/dL | 4.2 ± 0.3 | 4.3 ± 0.3 |
| Cholesterol, mg/dL | 197.1 ± 44.1 | 214.9 ± 40.5 |
| C-reactive protein, µg/mL | 4.1 ± 3.4 | 4.9 ± 9.0 |
| Interleukin 6, pg/mL | 3.0 ± 2.6 | 2.1 ± 3.9 |
| TNF-α, pg/mL | 1.8 ± 2.2 | 5.0 ± 2.5 |
Data are given as number (percent) for gender and specific diseases; all other variables are reported as mean ± standard deviation.
Abbreviations: ADL: activities of daily living; BMI: Body Mass Index; CPS: Cognitive Performance Scale; IADL: instrumental activities of daily living; MMSE: MiniMental State Examination; TNF: tumor necrosis factor.