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. 2017 Sep;9(Suppl 10):S1087–S1110. doi: 10.21037/jtd.2017.07.27

Table 1. Thermal effects on tissue at varying temperatures (50,51).

Effect Temperature (°C) Histopathological Effects
Hyperthermia 40 Reversible cell injury, conformational changes of cells, shrinking of collagen, deactivation of enzymes
Devitalization 42 Same as above
Coagulation 60 Denaturation of proteins, hyalinization of collagen, membrane permeability changes
Desiccation 100 Tissue drying, extracellular vacuoles, rupture of vacuoles
Carbonization 200 Tissue ablation and carbonization
Vaporization 300–1,000 Vaporization of carbon