Figure 7.

Spontaneous IPSPs reveal two components. (A) Spontaneous IPSPs (asterisks) were recorded during gap-free current-clamp mode from a torus type II hair cell. IPSPs were of a magnitude approaching the hyperpolarization generated by the application of 100 μM ACh (black bar). The fifth IPSP is enlarged to reveal its distinct kinetics (Scale bar: 10 mV, 500 ms). (B) Single IPSCs from another torus type II hair cell during voltage-clamp as the hair cell is held at different holding potentials. Two kinetic components can be identified at each potential. (C) Spontaneous IPSPs (asterisks) and hyperpolarizing response to 100 μM ACh were completely inhibited by 3 μM STR. (D,E) Currents in torus type II hair cells under gap-free, voltage clamp conditions were recorded during the application of an external solution containing 40 mM K⁺ (black) or 40 mM K⁺ external solution with either 10 μM ICS (gray, D) or 500 nM apamin (gray, E).