Table 2.
Prevalence of microcephaly by country and region, 2005-14
| Country and region (No of hospitals) | Hospital based | Population based | |||||
|---|---|---|---|---|---|---|---|
| Cases | Total births | Prevalence, per 10 000 (95% CI) |
Cases | Births | Prevalence, per 10 000 (95% CI) |
||
| Argentina (35): | 95 | 316 771 | 3.0 (2.4 to 3.7) | 39 | 237 702 | 1.6 (1.2 to 2.2) | |
| Buenos Aires (9) | 17 | 53 032 | 3.2 (1.8 to 5.1) | 4 | 43 420 | 0.92 (0.25 to 2.4) | |
| Centro (2) | 13 | 33 768 | 3.8 (2.1 to 6.6) | 6 | 27 793 | 2.2 (0.79 to 4.7) | |
| Cuyo (5) | 3 | 31 566 | 1.0 (0.20 to 2.8) | 2 | 26 609 | 0.75 (0.09 to 2.7) | |
| Nordeste (1) | 2 | 17 096 | 1.2 (0.14 to 4.2) | 2 | 17 096 | 1.2 (0.14 to 4.2) | |
| Noroeste (4) | 36 | 92 936 | 3.9 (2.7 to 5.4) | 6 | 45 718 | 1.3 (0.48 to 2.9) | |
| Pampa (9) | 23 | 80 233 | 2.9 (1.8 to 4.3) | 18 | 68 926 | 2.6 (1.6 to 4.1) | |
| Patagonia (5) | 1 | 8140 | 1.2 (0.03 to 6.8) | 1 | 8140 | 1.2 (0.03 to 6.8) | |
| Bolivia (5): | 18 | 80 322 | 2.2 (1.3 to 3.5) | 11 | 58 080 | 1.9 (0.95 to 3.4) | |
| Andes (4) | 14 | 52 372 | 2.7 (1.5 to 4.5) | 9 | 40 520 | 2.2 (1.0 to 4.2) | |
| Subandina (1) | 4 | 27 950 | 1.4 (0.4 to 3.7) | 2 | 17 560 | 1.1 (0.14 to 4.1) | |
| Brazil (22): | 251 | 303 922 | 8.3 (7.3 to 9.4) | 114 | 209 834 | 5.4 (4.5 to 6.5) | |
| Centro (1) | 1 | 3997 | 2.5 (0.06 to 13.9) | 1 | 3854 | 2.6 (0.07 to 14.5) | |
| Nordeste (4) | 76 | 90 891 | 8.4 (6.6 to 10.5) | 34 | 49 501 | 6.9 (4.8 to 9.6) | |
| Sudeste (11) | 144 | 88 052 | 16.4* (13.8 to 19.3) | 70 | 68 178 | 10.3 (8 to 12.9) | |
| Sul (6) | 30 | 120 982 | 2.5 (1.7 to 3.5) | 9 | 88 301 | 1.0 (0.47 to 1.9) | |
| Chile (11): | 89 | 192 401 | 4.6 (3.7 to 5.7) | 43 | 102 631 | 4.2 (3.0 to 5.6) | |
| Lagos (1) | 7 | 34 665 | 2.0 (0.81 to 4.2) | 5 | 23 229 | 2.2 (0.70 to 5.0) | |
| Maule (4) | 19 | 91 244 | 2.1 (1.3 to 3.3) | 12 | 49 915 | 2.4 (1.2 to 4.2) | |
| Metropolitana (6) | 63 | 66 492 | 9.5 (7.3 to 12.1) | 26 | 29 487 | 8.8 (5.8 to 12.9) | |
| Colombia (15): | 53 | 152 485 | 3.5 (2.6 to 4.6) | 41 | 122 437 | 3.3 (2.4 to 4.5) | |
| Caribe (1) | 2 | 1411 | 14.2 (1.7 to 51.2) | 1 | 1411 | 7.1 (0.18 to 39.5) | |
| Sabana (12) | 40 | 83 693 | 4.8 (3.4 to 6.5) | 34 | 69 115 | 4.9 (3.4 to 6.9) | |
| Valle (2) | 11 | 67 381 | 1.6 (0.8 to 2.9) | 6 | 51 911 | 1.2 (0.4 to 2.5) | |
| Ecuador (11): | 23 | 81 835 | 2.8 (1.8 to 4.2) | 10 | 63 085 | 1.6 (0.76 to 2.9) | |
| Costa (4) | 2 | 19 484 | 1.0 (0.1 to 3.7) | 0 | 16 666 | 0 (0 to 2.2) | |
| Sierra (7) | 21 | 62 351 | 3.4 (2.1 to 5.2) | 10 | 46 419 | 2.2 (1.0 to 3.9) | |
| Paraguay (1): | 1 | 5237 | 1.9 (0.05 to 10.6) | 0 | 1885 | 0 (0 to 19.6) | |
| Asuncion (1) | 1 | 5237 | 1.9 (0.05 to 10.6) | 0 | 1885 | 0 (0 to 19.6) | |
| Peru (1): | 6 | 19 881 | 3.0 (1.1 to 6.6) | 6 | 19 881 | 3.0 (1.1 to 6.6) | |
| Lima (1) | 6 | 19 881 | 3.0 (1.1 to 6.6) | 6 | 19 881 | 3.0 (1.1 to 6.6) | |
| Uruguay (2): | 0 | 9553 | 0 (0 to 3.9) | 0 | 9553 | 0 (0 to 3.9) | |
| Maldonado (1) | 0 | 1922 | 0 | 0 | 1922 | 0 | |
| Montevideo (1) | 0 | 7631 | 0 | 0 | 7631 | 0 | |
| Venezuela (4): | 16 | 84 778 | 1.9 (1.1 to 3.1) | 4 | 55 986 | 0.71 (0.19 to 1.8) | |
| Guyana (1) | 1 | 9868 | 1.0 (0.03 to 5.7) | 1 | 9868 | 1.0 (0.03 to 5.7) | |
| Occidente (1) | 13 | 54317 | 2.4 (1.3 to 4.1) | 2 | 25 525 | 0.78 (0.09 to 2.8) | |
| Zulia (2) | 2 | 20593 | 1.0 (0.12 to 3.5) | 1 | 20 593 | 0.49 (0.01 to 2.7) | |
| All countries (107) | 552 | 1 247 185 | 4.4* (4.1 to 4.9) | 268 | 881 074† | 3.0 (2.7 to 3.4) | |
*Removal of high prevalence tertiary A05 hospital from Brazil gives estimated hospital based prevalence for Brazil SE of 9.6/10 000 (95% CI 7.5 to 11.9; n=75; births=78 470) and all countries prevalence of 3.9/10 000 (3.6 to 4.3; n=483; births=1 237 603). A05 alone has hospital based prevalence of 72/10 000 (56.1 to 91; n=69; births=9582) and population based prevalence of 52.4/10 000 (36.3 to 76.1). Brazil SE population based prevalence without A05 is 2.7/10 000 (2.3 to 3.0).
†Estimated from 71% of controls residing within municipality of hospital (0.71*1 247 187=881 074).