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. Author manuscript; available in PMC: 2018 Apr 3.
Published in final edited form as: Thromb Haemost. 2017 Jan 26;117(4):671–681. doi: 10.1160/TH16-09-0691

Figure 1. Nucleic acids induce autoactivation of fXI but not PK.

Figure 1

(A) Plasma fXI (30 nM) or (B) PK (60 nM) was incubated with varying concentrations of genomic DNA or total cellular RNA for 15 (∆), 30 (□) or 60 (○) minutes. At designated times fXIa or kallikrein activity where measured by chromogenic assay. Error bars are +/− one SD.