Figure 1.
Body weight and gait scores changes induced by acrylamide (ACR) exposure.
Gait scores were examined in pregnant rats from all groups from the 6th day of pregnancy for 5 weeks. (A, B) Body weight of gravid and weaning rats decreased with increasing exposure time (mean ± SD, n = 8, one-way analysis of variance followed by Tukey post hoc test). *P < 0.05, **P < 0.01, vs. control group; #P < 0.05, vs. ACR 5 mg/kg group; ††P < 0.01, vs. ACR 10 mg/kg group. (C) Gait scores of gravid rats were increased with ACR exposure. The locomotion of gravid rats was impaired by ACR exposure (mean ± SD, n = 8, one-way analysis of variance followed by Tukey post hoc test). **P < 0.01, vs. control group; ##P < 0.01, vs. ACR 5 mg/kg group; ††P < 0.01, vs. ACR 10 mg/kg group. Higher gait scores represent increased motor function impairment.