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. 2017 Nov 21;11:107. doi: 10.1186/s12918-017-0496-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Flux distributions at key enzymes in the pfkA-mutant during shifts in glucose and oxygen concentration. Negative and positive fluxes represent backward and forward sense of the reaction. pgi: glucose-6-phosphate isomerase, serA: phosphoglycerate dehydrogenase, pckA: PEP carboxykinase, icd1/2: isocitrate dehydrogenase, frdA~D: fumarate reductase, mdh: malate dehydrogenase, fumC: fumarase, acn: aconitase, mutAB: methylmalonyl-CoA mutase, accA3: acetyl-CoA carboxylase, fgd1: glucose-6-phosphate dehydrogenase, pykA: pyruvate kinase