Table 4.

Multivariate analysis of prognostic factors

Prognostic factors	HR	95% CI	P value
Gender (male/female)	1.297	0.954–1.762	0.097
KPS (<80/≥80)	2.087	1.539–2.831	<0.001
Metachronous/Synchronous	0.685	0.489–0.961	0.028
ECM (N/Y)	0.749	0.054–1.012	0.060
Histology (non-adenocarcinoma/adenocarcinoma)	1.303	1.114–1.524	0.001

MST median survival time, KPS Karnofsky performance status, ECM extracranial metastases