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. 2017 Nov 21;17:107. doi: 10.1186/s12935-017-0481-z

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — PTC-209 inhibited cell migration and invasion of HNSCC cells. a Cell migration was significantly reduced in cells treated with PTC-209 (10 μM, 24 h) as measured in wound healing assay. Scale bar: 200 μm. b Cell invasiveness was pronouncedly impaired in cells treated with PTC-209 (10 μM, 24 h) as measured in the transwell assay. Scale bar: 50 μm. c The amount of E-cadherin was increased and N-cadherin and vimentin was downregulated simultaneously in cells treated with PTC-209 (10 μM, 48 h). Representative images are shown. Data showed here are mean ± SD from three independent experiments