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. 2017 Nov 7;2017:1923505. doi: 10.1155/2017/1923505

Table 1.

Reports on the use of the AngioVac device in treatment of RSIE.

Author/year Type of publication Age/sex Organism Location of vegetation Indication for procedure Preprocedural vegetation size Reduction in vegetation size Postprocedural bacteremia Tricuspid regurgitation (TR) progression Outcome
Todoran et al. [20] (2011) Case report 53 y/o, M Haemophilus parainfluenzae SVC/RA junction Lack of response to appropriate antimicrobial therapy 1.7 cm 100% removal Resolved Not reported Improvement with no further sequel

Jones et al. [21] (2017) Case report 25 y/o, F Candida albicans (i) SV/RA junction attached to ICD RV lead (i) Persistent fungemia despite appropriate antimicrobial therapy SV/RA junction: 6.1 cm × 1.65 cm Removal of 6 cm vegetation (residual vegetation size not reported) Resolved Not reported Improvement with no further sequel
(ii) RA (ii) Recurrent septic emboli RA: −2.1 cm × 1.6 cm

Schaerf et al. [10] (2016) Retrospective study (20 patients) Mean age: 76 ± 11 8 coagulase-negative SA 13 ICD; 7 pacemaker (i) Lack of response to appropriate antimicrobial therapy Average size: 3.6 cm ± 1.2 cm Not mentioned Resolved in 19/20 patients Not reported Not reported clearly
3 MSSA
4 MRSA
3 Streptococci
Sex not reported
1 Enterococcus
1 Polymicrobial
(ii) Bridge to percutaneous lead removal

Thiagaraj et al. [22] (2017) Case series Patient 1: 35 y/o, M MSSA SVC/RA junction extending into TV (i) Lack of response to appropriate antimicrobial therapy 4.5 cm 100% removal Resolved Not reported Improvement with no further sequel
(ii) Vegetation size ≥ 20 mm
Patient 2: 28 y/o, F MRSA TV (i) Lack of response to appropriate antimicrobial therapy 2.2 × 1.7 cm 100% removal Resolved Not reported MRSA bacteremia recurrence, cardiac arrest, and death 5 days post procedure
(ii) Vegetation size ≥ 20 mm
Patient 3: 53 y/o, F Enterococcus faecalis Bioprosthetic TV (i) Vegetation size ≥ 20 mm 3.2 cm 25–50% reduction in size Resolved Improvement from moderate to mild Improvement with mild worsening of TR
(ii) Worsening of TV regurgitation

Divekar et al. [7] (2013) Case report 17 y/o, M MSSA Pulmonary valve Recurrent pulmonary embolism despite antimicrobial therapy 3.5 cm × 1.5 cm Significant reduction (residual vegetation size not reported) Resolved Not reported Clinical improvement with no further sequel

George et al. [23] (2017) Retrospective study (33 patients) Mean age: 37 ± 12 14 MRSA TV Lack of response to appropriate antimicrobial therapy 2.1 cm ± 0.7 cm Average of 61% reduction in size Resolved in 28/33 patients 14 patients: worsening of TR (3 required elective TV repair) 28 patients: improvement with no further sequel
11 MSSA
12, M 3 polymicrobial 1 patient: developed postprocedural cardiac tamponade requiring pericardiocentesis
21, F 5 Candida 3 patients: death

Makdisi et al. [16] (2016) Case report 24 y/o, M MRSA TV Lack of response to appropriate antimicrobial therapy 0.9 cm × 0.7 cm 80% reduction in size Resolved No change Clinical improvement with no further sequel
0.7 cm × 1 cm

Patel et al. [11] (2013) Case series Patient 1: 59 y/o, M SA ICD lead (i) Vegetation size ≥ 20 mm 3 cm × 2 cm Significant reduction (residual vegetation size not reported) Resolved Improvement in degree of TR Clinical improvement with no further sequel
(ii) Bridge to percutaneous lead removal
Patient 2: 82 y/o, M Group B Streptococcus (i) Pacemaker lead (i) Vegetation size ≥ 20 mm (i) Pacemaker lead: 4 cm × 1.5 cm Significant reduction (residual vegetation size not reported) Not reported Not reported Not reported
(ii) TV (ii) Bridge to percutaneous lead removal (ii) TV: 0.5 cm × 1.1 cm
Patient 3: 56 y/o, F MRSA Pacemaker lead (i) Vegetation size ≥ 20 mm 3.5 cm × 1.7 cm Significant reduction (residual vegetation size not reported) Persistent bacteremia Worsening of TR Formation of new vegetation with severe TR that required TV repair
(ii) Bridge to percutaneous lead removal

Dalia et al. [12] (2016) Case report 26 y/o, F Not reported TV Bridge to pulmonary artery aneurysm repair 1.6 cm × 0.8 cm Significant reduction (residual vegetation size not reported) Not reported Not reported Underwent pulmonary artery aneurysm repair successfully; clinical improvement with no further sequel

Hosoba et al. [24] (2015) Case series Patient 1: 67 y/o, F MRSA RA Not reported 1.5 cm × 1.5 cm Not reported Resolved Not reported Clinical improvement with no further sequel
Patient 2: 33 y/o, M Enterobacter cloacae RA near Chiari network Not reported 2.2 cm × 0.6 cm Not reported Resolved Not reported Clinical improvement with no further sequel
Patient 3: 70 y/o, M MSSA SVC/RA junction Vegetation size  20 mm 3.4 cm × 1.3 cm Not reported Resolved Not reported Clinical improvement with no further sequel

M: male, F: female, y/o: years old, SVC: superior vena cava, RA: right atrium, ICD: implantable cardioverter defibrillator, RV: right ventricle, SA: Staphylococcus aureus, MSSA: methicillin-sensitive Staphylococcus aureus, MRSA: methicillin-resistant Staphylococcus aureus, TV: tricuspid valve, TR: tricuspid regurgitation.