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. 2017 Nov 21;15:84. doi: 10.1186/s12951-017-0320-3

Table 3.

Limitations that hinder the broad use of omics technologies in nanotoxicology

Independent from the technology Technology linked
Lack of standardization of particle exposure Request for high sample quality (freezing, protection against degradation)
 Sample pre-treatment Expertise in bioinformatics needed for data analysis
 Cell type used for testing Lack of standardization of sample preparation
 Medium composition Predictive value of the omics techniques not entirely clear
Relevant concentration range