Table 2.
Biochemic and urinary findings in the three groups of dogs included in the study
| Group | A | B | C | |||
|---|---|---|---|---|---|---|
| Day | 1 | 7 | 14 | 21 | ||
| Urea (mg/dL) | 22.69 ± 7.67 | 28.26 ± 4.96 | 26.75 ± 8.49 | 24.55 ± 4.68* | 45.66 ± 34.93 | 34.31 ± 8.35 |
| ALT (UI/L) | 31.8 ± 28.8 | 43.7 ± 4.03 | 104.4 ± 27.77** | 59.3 ± 9.85 | 95.95 ± 16.19** | 33.68 ± 2.86 |
| Creatinine (mg/dL) | 0.82 ± 0.07 | 0.69 ± 0.07* | 0.83 ± 0.08 | 0.86 ± 0.14 | 0.97 ± 0.71 | 0.96 ± 0.12 |
| TP (g/dL) | 6.2 ± 0.1 | 6.4 ± 0.2 | 6.2 ± 0.1 | 6.4 ± 0.1 | 6.9 ± 0.1** | 6.4 ± 0.1 |
| Albumin (g/L) | 0.37 ± 0.01 | 0.38 ± 0.02 | 0.38 ± 0.02 | 0.37 ± 0.02 | 0.39 ± 0.01 | 0.36 ± 0.01 |
| Cholesterol (mg/dL) | 210.65 ± 27.08 | 280.04 ± 48.23** | 324.43 ± 45.43 | 237.50 ± 39.48 | 315.53 ± 131.52** | 186.19 ± 60.35 |
| ALP (UI/L) | 227.3 ± 27.97** | 360 ± 46.14** | 456 ± 61.8** | 306.7 ± 36.6** | 494.35 ± 79.15** | 63.68 ± 5.40 |
| Calcium (mg/dL) | 11.07 ± 0.78* | 11.18 ± 0.66* | 11.09 ± 0.71* | 11.14 ± 0.60* | 9.49 ± 0.44 | 9.95 ± 1.29 |
| Phosphorus (mmol/L) | 3.96 ± 0.19 | 4.00 ± 0.19 | 4.00 ± 0.25 | 3.93 ± 0.22 | 4.31 ± 0.12 | 3.78 ± 0.15 |
| UP/C | 0.24 ± 0.02 | 0.26 ± 0.02 | 0.22 ± 0.02 | 0.25 ± 0.02 | 0.35 ± 0.02** | 0.2 ± 0.02 |
Serum urea, ALT, total protein (TP), albumin, cholesterol, ALP, calcium, phosphorus, and UP/C (urinary protein/creatinine ratio) values in dogs affected with steroid responsive meningitis arteritis (SRMA; group A, at days 1, 7, 14, and 21 after treatment onset, n = 10), dogs with hyperadrenocorticism (PDH; group B, n = 20), and control dogs (group C, n = 16). Values are presented as mean ± SEM. Values marked with * differ statistically from the control group: *P < 0.05 and **P < 0.01.