Table 1.

In vivo toxicity studies of enniatin B (ENN B).

Animal	Dosage/route	Effects	Reference
Broiler chicken	0.2 mg/kg b.w.	Tissue bioaccumulation	Fraeyman et al. (63)
	Bolus
Mice	5 mg/kg b.w.of ENN B	No acute damage	Rodríguez-Carrasco et al. (22)
	Intraperitoneal on two consecutive days	Tissue bioaccumulation
Mice	1.25–40 mg/kg b.w. (every 8 h)	Mice died in 2–5 days (10–40 mg/kg b.w.)	McKee et al. (19)
	Intraperitoneal	Reduction of weight
		No anti-HIV activity
Pigs	0.05 mg/kg b.w.	Absorption	Devreese et al. (62)
	Oral bolus	ENN B > B1 > A1 > A
Wistar rats	Mixture of ENNs containing 1.19, 2.16, 1.03 and 1.41 mg/kg b.w.of ENN A, A1, B, and B1	No adverse effect	Escrivá et al. (23)
	Oral