Table 1.
Cytotoxic effect of Andosan on myeloma cells from 8 patients. The numbers of viable cells after 72 hrs of culture were noted and converted to per cent of controls (100%). Mean: mean of duplicates; SE: standard error. Comparison of means of controls versus means of cultures with Andosan 4% showed a statistically significant difference (p = 0.01).
| Patient number | Control | Andosan 0.5% | Andosan 1.0% | Andosan 2.0% | Andosan 4.0% |
|---|---|---|---|---|---|
| 139 | |||||
| Mean | 100 | 93.69 | 99.12 | 97.61 | 80.47 |
| SE | 4.04 | 1.35 | 1.11 | 2.11 | 0.44 |
| 244 | |||||
| Mean | 100 | 117.91 | 122.5 | 114.15 | 110.22 |
| SE | 1.33 | 2.07 | 2.1 | 4.19 | 2.13 |
| 969 | |||||
| Mean | 100 | 65.73 | 62.3 | 55.42 | 52.37 |
| SE | 1.95 | 2.18 | 2.22 | 2.66 | 2.39 |
| 185 | |||||
| Mean | 100 | 86.6 | 83.14 | 73.71 | 52.28 |
| SE | 0.88 | 1.38 | 0.66 | 1.82 | 0.77 |
| 409 | |||||
| Mean | 100 | 69.24 | 55.75 | 50.6 | 17.66 |
| SE | 1.5 | 2.05 | 2.05 | 2.05 | 2.18 |
| 715 | |||||
| Mean | 100 | 90.35 | 86.8 | 84.12 | 73.11 |
| SE | 1.54 | 1.73 | 2.72 | 0.92 | 1.21 |
| 2925 | |||||
| Mean | 100 | 91.81 | 90.92 | 80.78 | 54.27 |
| SE | 0.87 | 3.4 | 2.19 | 1.88 | 1.88 |
| 355 | |||||
| Mean | 100 | 82.22 | 85.21 | 78.34 | 70.77 |
| SE | 2.17 | 2.64 | 2.39 | 3.15 | 2.95 |