Table 4.
Groups | Paw withdrawal latency (%) | |||||
---|---|---|---|---|---|---|
0 d | 7 d | 14 d | 21 d | 28 d | 35 d | |
Control | 100.0 | 99.2 ± 3.5 | 99.4 ± 5.5 | 98.7 ± 4.2 | 97.6 ± 3.4 | 99.1 ± 6.2 |
AIA group | 100.0 | 35.4 ± 5.3∗∗ | 33.6 ± 7.6∗∗ | 32.4 ± 5.5∗∗ | 32.0 ± 6.2∗∗ | 30.1 ± 4.8∗∗ |
DEX (5 mg/kg) | 100.0 | 44.4 ± 6.9# | 52.7 ± 6.8## | 63.5 ± 9.1## | 65.8 ± 8.5## | 72.3 ± 11.7## |
QWRG | ||||||
1.0 g/kg | 100.0 | 35.4 ± 5.7 | 36.3 ± 9.6 | 37.4 ± 7.6 | 36.8 ± 6.8 | 37.1 ± 8.2 |
2.0 g/kg | 100.0 | 37.7 ± 6.8 | 42.8 ± 7.8##& | 52.9 ± 9.2##& | 51.5 ± 6.9##& | 53.6 ± 8.1##& |
4.0 g/kg | 100.0 | 41.4 ± 6.4# | 45.5 ± 6.4## | 58.8 ± 7.3## | 60.2 ± 8.15## | 60.1 ± 5.9## |
The values from 10 different rats in each group. Data are mean ± SD. ∗∗P < 0.01 versus control; #P < 0.05, ##P < 0.01 versus model; &P < 0.05 versus DEX.