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. 2017 Nov 21;14:227. doi: 10.1186/s12974-017-0995-2

Fig. 3.

Fig. 3

NAIVE-AS, EAE-AS, and anti-MOG binding on BrdU+ cells in normal mouse brain in three age groups. ac SVZ sections of neonates, eg postnates, and i, j, k adults double-stained with anti-BrdU and NAIVE-AS, EAE-AS, and anti-MOG, respectively. Arrows denote the double positive cells for BrdU+/EAE-AS+ and BrdU+/anti-MOG+. Scale bars=200 μm. dl Graphs represent the corresponding anti-BrdU co-expression % with NAIVE-AS, EAE-AS, and anti-MOG. BrdU+/EAE-AS+ cell populations are widespread in three age groups versus BrdU+/anti-MOG+, especially in postnates (* p < 0.05, ** p < 0.01, *** p < 0.001)