Table 3.
Cell lines | IC50 (µM) | |
---|---|---|
Rc | Ro | |
Caco-2 | 32.16 | 39.51147 |
HCT 116 | 29.14 | 51.4279 |
HepG2 | 29.1 | 53.9 |
MCF7 | 46.15 | > 100 |
BHK | > 100 | 49.75148 |
Caco-2 vs BHK-21 | 3.10 ** | 1.25 |
HCT 116 vs BHK-21 | 3.43 ** | 0.96 |
HepG2 vs BHK-21 | 3.43 ** | 0.92 |
MCF7 vs BHK-21 | 2.16 * | 0.49 |
Notes: Rc, Moringa root core; Ro, Moringa root outer; IC50, The half maximal inhibitory concentration
the fold change in the cytotoxic effects of Rc on the cancer cell lines (Caco-2, HCT 116, HepG2) were over 3 times of its effect on the normal BHK-21 one
the fold change in the cytotoxic effect of Rc on the breast cancer MCF7 cells was over 2 times of its effect on the normal BHK-21 one.