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. 2017;18(8):2141–2149. doi: 10.22034/APJCP.2017.18.8.2141

Table 3.

The Inhibitory Effect (IC50) of Moringa Rc and Ro on Various Cell Lines

Cell lines IC50 (µM)
Rc Ro
Caco-2 32.16 39.51147
HCT 116 29.14 51.4279
HepG2 29.1 53.9
MCF7 46.15 > 100
BHK > 100 49.75148
Caco-2 vs BHK-21 3.10 ** 1.25
HCT 116 vs BHK-21 3.43 ** 0.96
HepG2 vs BHK-21 3.43 ** 0.92
MCF7 vs BHK-21 2.16 * 0.49

Notes: Rc, Moringa root core; Ro, Moringa root outer; IC50, The half maximal inhibitory concentration

**

the fold change in the cytotoxic effects of Rc on the cancer cell lines (Caco-2, HCT 116, HepG2) were over 3 times of its effect on the normal BHK-21 one

*

the fold change in the cytotoxic effect of Rc on the breast cancer MCF7 cells was over 2 times of its effect on the normal BHK-21 one.