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. 2017;18(8):2255–2268. doi: 10.22034/APJCP.2017.18.8.2255

Table 1.

Effect at PLL on Ascite Fluid Volume, Packed Cell Volume, Body Weight, Mean Survival Time (MST), Percentage Increased Life Span (% ILS), Viable and non-Viable Tumor Cell Count in EAC Bearing Mice

Poly L-lysine 20 mg/kg b.w Poly L-lysine 40 mg/kg b.w Std drug 20 mg/kg b.w EAC Control(2 x 106 cells/mouse)
Ascite fluid volume (ml.) 6.63 ± 0.18* 4.6 ± 0.04* 5.18 ± 0.29* 11.55 ± 0.05*
Packed Cell volume (ml.) 2.73 ± 0.03* 1.45 ± 0.03* 1.34 ± 0.01* 3.97 ± 0.04*
Body Weight (gm.) 23.64 ± 0.24* 17.08 ± 0.08* 20.4 ± 0.25* 30.6 ± 0.27*
MST (days) 30.86 ± 0.43* 40.55 ± 0.04* 53.05 ± 0.04* 20.14 ± 0.02*
% ILS 56.25 ± 0.04 88.35 ± 0.05 112.35 ± 0.03 0 ± 0
Viable cell (x 106 cells/ml) 3.05 ± 0.03* 1.23 ± 0.02* 3.32 ± 0.03* 10.07 ± 0.04*
Nonviable cell (106 cells/ml) 3.98 ± 0.17* 3.79 ± 0.14* 3.99 ± 0.12* 0.67 ± 0.06*

Each point represent the mean ±SEM. (n=6 mice per group); *p<0.05 statistically significant when compared with EAC control group.