Table 1.
Poly L-lysine 20 mg/kg b.w | Poly L-lysine 40 mg/kg b.w | Std drug 20 mg/kg b.w | EAC Control(2 x 106 cells/mouse) | |
---|---|---|---|---|
Ascite fluid volume (ml.) | 6.63 ± 0.18* | 4.6 ± 0.04* | 5.18 ± 0.29* | 11.55 ± 0.05* |
Packed Cell volume (ml.) | 2.73 ± 0.03* | 1.45 ± 0.03* | 1.34 ± 0.01* | 3.97 ± 0.04* |
Body Weight (gm.) | 23.64 ± 0.24* | 17.08 ± 0.08* | 20.4 ± 0.25* | 30.6 ± 0.27* |
MST (days) | 30.86 ± 0.43* | 40.55 ± 0.04* | 53.05 ± 0.04* | 20.14 ± 0.02* |
% ILS | 56.25 ± 0.04 | 88.35 ± 0.05 | 112.35 ± 0.03 | 0 ± 0 |
Viable cell (x 106 cells/ml) | 3.05 ± 0.03* | 1.23 ± 0.02* | 3.32 ± 0.03* | 10.07 ± 0.04* |
Nonviable cell (106 cells/ml) | 3.98 ± 0.17* | 3.79 ± 0.14* | 3.99 ± 0.12* | 0.67 ± 0.06* |
Each point represent the mean ±SEM. (n=6 mice per group); *p<0.05 statistically significant when compared with EAC control group.