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Correlation Analysis of Gal-9 and PD-L1 mRNA Expression with the Frequency of Tim-3+ or PD-1+ T lymphocytes in CLL patients. Gal-9 mRNA expression was significantly associated with the frequency of Tim-3+/CD8+ T cells (r = 0.426, p = 0.04) (4A). PD-L1 mRNA expression was also significantly correlated with the frequency of PD-1+/CD4+ T cells in CLL patients (r = 0.608, p = 0.001) (4B).
