Table 2.
Correlation between Clinicopathological Features, TGM2, TXNIP Expression, Ki Labeling Index of Our Patients
| Characteristics | All | TGM2 | p-value | TXNIP | p-value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | High | Low | High | |||||||||
| (N=50) | (N=29) | (N=21) | (N=22) | (N=28) | ||||||||
| No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | |||
| Age (years) | ||||||||||||
| Mean ± SD | 42.34 ±11.59 | 40.34 ±10.70 | 45.09 ±12.46 | 0.155* | 45.45 ±11.89 | 39.89 ±10.95 | 0.093* | |||||
| Median (Range) | 39.5 | (24-65) | 39 | (24-65) | 43 | (24-65) | 44 | (24-65) | 39 | (24-65) | ||
| < 40 years | 26 | (52%) | 18 | (69.20%) | 8 | (30.80%) | 0.094‡ | 7 | (26.90%) | 19 | (73.10%) | 0.011‡ |
| > 40 years | 24 | (48%) | 11 | (45.80%) | 13 | (54.20%) | 15 | (62.50%) | 9 | (37.50%) | ||
| Sex | ||||||||||||
| Male | 15 | (30%) | 5 | (33.30%) | 10 | (66.70%) | 0.021‡ | 12 | (80%) | 3 | (20%) | 0.001‡ |
| Female | 35 | (70%) | 24 | (68.60%) | 11 | (31.40%) | 10 | (28.60%) | 25 | (71.40%) | ||
| Site | ||||||||||||
| Parasagittal | 14 | (28%) | 12 | (85.70%) | 2 | (14.30%) | 0.117‡ | 3 | (21.40%) | 11 | (78.60%) | 0.262‡ |
| Anterior Fossa | 12 | (24%) | 7 | (58.30%) | 5 | (41.70%) | 5 | (41.70%) | 7 | (58.30%) | ||
| Convexity | 8 | (16%) | 3 | (37.50%) | 5 | (62.50%) | 5 | (62.50%) | 3 | (37.50%) | ||
| Middle fossa | 8 | (16%) | 4 | (50%) | 4 | (50%) | 4 | (50%) | 4 | (50%) | ||
| Posterior fossa | 8 | (16%) | 3 | (37.50%) | 5 | (62.50%) | 5 | (62.50%) | 3 | (37.50%) | ||
| Calcification | ||||||||||||
| Absent | 28 | (56%) | 14 | (50%) | 14 | (50%) | 0.196‡ | 13 | (46.40%) | 15 | (53.60%) | 0.696‡ |
| Present | 22 | (44%) | 15 | (68.20%) | 7 | (31.80%) | 9 | (40.90%) | 13 | (59.10%) | ||
| Grade | ||||||||||||
| Grade I | 31 | (62%) | 24 | (77.40%) | 7 | (22.60%) | 0.002§ | 6 | (19.40%) | 25 | (80.60%) | <0.001§ |
| Grade II | 12 | (24%) | 3 | (25%) | 9 | (75%) | 9 | (75%) | 3 | (25%) | ||
| Grade III | 7 | (14%) | 2 | (28.60%) | 5 | (71.40%) | 7 | (100%) | 0 | 0%) | ||
| Ki67 | ||||||||||||
| Low | 30 | (60%) | 24 | (80%) | 6 | (20%) | <0.001‡ | 5 | (16.70%) | 25 | (83.30%) | <0.001‡ |
| High | 20 | (40%) | 5 | (25%) | 15 | (75%) | 17 | (85%) | 3 | (15%) | ||
| TGM2 | ||||||||||||
| Low | 29 | (58%) | 3 | (10.30%) | 26 | (89.70%) | <0.001‡ | |||||
| High | 21 | (42%) | 19 | (90.50%) | 2 | (9.50%) | ||||||
| TXNIP | ||||||||||||
| Low | 22 | (44%) | 3 | (13.60%) | 19 | (86.40%) | <0.001‡ | |||||
| High | 28 | (56%) | 26 | (92.90%) | 2 | (7.10%) | ||||||
Categorical variables were expressed as number (percentage), continuous variables were expressed as mean ± SD & median (range)
*
Independent samples Student’s t-test
‡
Chi-square test
§
Chi-square test for trend; p< 0.05 is significant.