Table 1.
Primary Sponsoring Company | INN or Code Name | Molecular Format | Target | Most Advanced Phase | Indications |
---|---|---|---|---|---|
Alder Biopharmaceuticals | ALD403/eptinezumab | Humanized IgG1 | CGRP | Phase 3 | Migraine prevention |
Eli Lilly and Company | LY2951742/galcanezumab | Humanized IgG4 | CGRP | Phase 3 | Migraine and cluster headache prevention |
Teva Pharmaceuticals | TEV‐48125/frestanezumab | Humanized IgG2 | CGRP | Phase 3 | Migraine prevention |
Amgen/Novartis | AMG 334/erenumab | Human IgG2 | CGRP receptor | Phase 3 | Migraine prevention |
INN, international nonproprietary name; CGRP, calcitonin gene–related peptide.