Table 1.
Baseline clinical parameters
| All CLARIFY Patients, n = 32 703 | Prior MI >3 Months Ago,a n = 18 876 (57.7%) | Coronary Stenosis ≥50% on Angiography,a n = 19 996 (61.1%) | Chest Pain With Proven Myocardial Ischemia,a n = 7544 (23.1%) | History of PCI or CABG >3 Months Ago,a n = 22 836 (69.8%) | |
|---|---|---|---|---|---|
| Age, y | 64.2 ± 10.5 | 63.1 ± 10.7 | 64.1 ± 10.4 | 64.6 ± 10.2 | 64.2 ± 10.4 |
| Male sex | 25 365 (77.6) | 15 246 (80.8) | 15 877 (79.4) | 5571 (73.9) | 18 291 (80.1) |
| Ethnicity | |||||
| Caucasian | 21 112 (64.6) | 12 873 (68.2) | 12 124 (60.6) | 4772 (63.3) | 14 342 (62.8) |
| South Asian | 2444 (7.5) | 1336 (7.1) | 1549 (7.7) | 539 (7.1) | 1645 (7.2) |
| Chinese | 2753 (8.4) | 1242 (6.6) | 1938 (9.7) | 330 (4.4) | 2040 (8.9) |
| Japanese/Korean | 1035 (3.2) | 401 (2.1) | 685 (3.4) | 103 (1.4) | 853 (3.7) |
| Hispanic | 1624 (5.0) | 1008 (5.3) | 1058 (5.3) | 580 (7.7) | 1171 (5.1) |
| Black/African | 357 (1.1) | 247 (1.3) | 217 (1.1) | 94 (1.2) | 225 (1.0) |
| Unknown | 3378 (10.3) | 1769 (9.4) | 2425 (12.1) | 1126 (14.9) | 2560 (11.2) |
| BMI, kg/m2 | 27.3 (24.8–30.4) | 27.5 (25.0–30.5) | 27.2 (24.8–30.1) | 27.6 (25.0–30.5) | 27.2 (24.8–30.1) |
| Waist circumference, cm | 97 (89–105) | 97 (89–105) | 97 (89–105) | 97 (89–105) | 97 (89–105) |
| Family history of premature CAD | 9326 (28.5) | 5503 (29.2) | 5621 (28.1) | 2576 (34.2) | 6443 (28.2) |
| Treated hypertension | 23 210 (71.0) | 13 029 (69.1) | 14 231 (71.2) | 5619 (74.5) | 16 122 (70.6) |
| DM | 9502 (29.1) | 5388 (28.6) | 5956 (29.8) | 2277 (30.2) | 6799 (29.8) |
| Dyslipidemia | 24 504 (74.9) | 14 383 (76.2) | 15 318 (76.6) | 5991 (79.5) | 17 465 (76.5) |
| Smoking status | |||||
| Current | 4077 (12.5) | 2700 (14.3) | 2391 (12.0) | 870 (11.5) | 2706 (11.9) |
| Former | 15 109 (46.2) | 9263 (49.1) | 9570 (47.9) | 3281 (43.5) | 11 038 (48.3) |
| Never | 13 513 (41.3) | 6911 (36.6) | 8032 (40.2) | 3391 (45.0) | 9088 (39.8) |
| Alcohol intake (drinks per week)b | |||||
| 0 | 15 613 (47.8) | 8813 (46.7) | 9562 (47.8) | 3451 (45.8) | 10 797 (47.3) |
| 1–19 | 15 898 (48.6) | 9305 (49.3) | 9743 (48.7) | 3778 (50.1) | 11 269 (49.4) |
| 20–40 | 1068 (3.3) | 688 (3.6) | 617 (3.1) | 279 (3.7) | 684 (3.0) |
| >40 | 113 (0.3) | 67 (0.4) | 65 (0.3) | 29 (0.4) | 75 (0.3) |
| Stimulant drinks consumed | |||||
| Coffee | 15 500 (47.4) | 8842 (46.9) | 9642 (48.3) | 3502 (46.6) | 11 438 (50.1) |
| Tea | 10 040 (30.7) | 6247 (33.1) | 5594 (28.0) | 2254 (30.0) | 6195 (27.2) |
| Neither | 7129 (21.8) | 3774 (20.0) | 4733 (23.7) | 1763 (23.4) | 5178 (22.7) |
| Intake of stimulant drinks, cups/d | 2 (2–4) | 2 (2–4) | 2 (2–4) | 2 (2–4) | 2 (2–4) |
| Employment status | |||||
| Employed full‐time | 7980 (24.4) | 4955 (26.3) | 5038 (25.2) | 1814 (24.1) | 5659 (24.8) |
| Employed part‐time | 2266 (6.9) | 1435 (7.6) | 1284 (6.4) | 520 (6.9) | 1471 (6.4) |
| Unable to work | 1284 (3.9) | 902 (4.8) | 802 (4.0) | 337 (4.5) | 846 (3.7) |
| Unemployed | 1852 (5.7) | 1079 (5.7) | 1062 (5.3) | 400 (5.3) | 1234 (5.4) |
| Retired | 18 081 (55.3) | 9860 (52.2) | 10 979 (54.9) | 4173 (55.4) | 12 721 (55.7) |
| Other | 1232 (3.8) | 640 (3.4) | 824 (4.1) | 294 (3.9) | 897 (3.9) |
| Weekly physical activity | |||||
| None | 5287 (16.2) | 2899 (15.4) | 3094 (15.5) | 1323 (17.6) | 3640 (15.9) |
| Light activity most weeks | 16 810 (51.4) | 9970 (52.8) | 10 071 (50.4) | 3821 (50.7) | 11 264 (49.4) |
| ≥20 minutes vigorous activity 1–2 times per week | 5470 (16.7) | 3130 (16.6) | 3432 (17.2) | 1277 (16.9) | 3968 (17.4) |
| ≥20 minutes vigorous activity ≥3 times per week | 5121 (15.7) | 2870 (15.2) | 3387 (16.9) | 1115 (14.8) | 3950 (17.3) |
| Education level | |||||
| Primary school (or less) | 8648 (26.5) | 4836 (25.6) | 5495 (27.5) | 1972 (26.2) | 6245 (27.4) |
| Secondary school | 15 204 (46.5) | 8797 (46.6) | 9119 (45.6) | 3499 (46.4) | 10 535 (46.2) |
| College/university | 8841 (27.0) | 5238 (27.8) | 5373 (26.9) | 2065 (27.4) | 6046 (26.5) |
Abbreviations: BMI, body mass index; CABG, coronary artery bypass graft; CAD, coronary artery disease; CLARIFY, Prospective Observational Longitudinal Registry of Patients With Stable Coronary Artery Disease; DM, diabetes mellitus; IQR, interquartile range; MI, myocardial infarction; PCI, percutaneous coronary intervention; SD, standard deviation.
Data are presented as n (%), mean ± SD, or median (IQR).
a
Inclusion criteria are not mutually exclusive; some patients may be included in >1 group.
b
1 drink = 1 standard measure of spirits, 1 glass of wine, 1 bottle of beer.