Table 1.
The identified spore wall proteins of Microsporidia
| Protein | Source | Mw (kDa) | Full length (nt)/amino acids (aa) | PI | Signal peptide/length (aa) | Phosphorylation/N‐glycosylation/O‐glycosylation | Subcellular localization | Functional domain | References/GenBank ID |
|---|---|---|---|---|---|---|---|---|---|
| EiSWP1 | Encephalitozoon intestinalis | 41.5 | 1167/388 | 4.78 | Yes/18 | 36/1/37 | External wall | – | Hayman et al. (2001); AF355750.1 |
| EiSWP2 | E. intestinalis | 107.2 | 3009/1002 | 3.68 | Yes/18 | 83/1/1 | External wall | – | Hayman et al. (2001); AF355749.1 |
| EiEnP1 | E. intestinalis | 39.1 | 1047/348 | 8.84 | Yes/16 | 28/3/1 | Internal wall/external wall/polar membrane layer | HBM | Corradi et al. (2010) and Pombert et al. (2012); XM_003072248 |
| ErEnP1 | E. romaleae | 39.5 | 1047/348 | 9.12 | Yes/16 | 15/3/3 | – | HBM | Pombert et al. (2012); XM_009265627.1 |
| EcSWP1 | Encephalitozoon cuniculi | 45.9 | 1353/450 | 4.96 | Yes/18 | 66/0/52 | External wall | – | Katinka et al. (2001); NM_001042116.1 |
| EcCDA | E. cuniculi | 28.1 | 765/254 | 4.43 | Yes/15 | 16/0/0 | Endospore plasma membrane | Glycoside hydrolase/Deacetylase | Brosson et al. (2005); NC_003237.1 |
| EcEnP1 | E. cuniculi | 40.6 | 1074/357 | 9.07 | Yes/16 | 20/1/3 | Endospore | HBM | Katinka et al. (2001) and Peuvel‐Fanget et al. (2006); XM_960824 |
| EcEnP2/SWP3 | E. cuniculi | 22.5 | 666/221 | 8.42 | Yes/20 | 31/0/27 | Endospore/plasmalemma | Transmembrane | Katinka et al. (2001), Peuvel‐Fanget et al. (2006), and Xu et al. (2006); NC_003242.2 |
| EhSWP1a | Encephalitozoon hellem | 54.9 | 1530/509 | 4.30 | Yes/18 | 38/3/27 | Extracellular spores | – | Polonais et al. (2010); FJ870923 |
| EhSWP1b | E. hellem | 57.9 | 1602/533 | 4.64 | Yes/18 | 44/3/29 | Extracellular spores | – | Polonais et al. (2010); FJ870924 |
| NbSW16 | Nosema bombycis | 22.5 | 666/221 | 8.42 | Yes/15 | 34/2/29 | Exospore | HBM | Wang et al. (2015); KB908937.1 |
| NbHSWP11 | N. bombycis | 52.3 | 1341/446 | 9.27 | No | 32/0/1 | Internal wall/external wall | DnaJ domain | Yang et al. (2014); EF683111 |
| SWP5 | N. bombycis | 20.3 | 561/186 | 4.39 | Yes/22 | 13/0/6 | Exospore/polar tube | – | Li et al. (2012); HQ881497 |
| NbSWP12 | N. bombycis | 26.6 | 687/228 | 6.78 | No | 13/1/0 | Internal wall/external wall | BAR‐2 domain | Chen et al. (2013); KC193258 |
| SWP25/HSWP2 | N. bombycis | 30.7 | 807/268 | 8.45 | Yes/25 | 15/2/6 | Endospore | HBM | Wu et al. (2008, 2009); EF683102 |
| SWP26 | N. bombycis | 25.7 | 672/223 | 5.09 | Yes/16 | 13/0/0 | Endospore/plasma membrane/exospore | HBM | Li et al. (2009); EU677842 |
| SWP30/HSWP1 | N. bombycis | 32.1 | 837/278 | 7.95 | Yes/19 | 22/1/4 | Endospore | – | Wu et al. (2008); EF683101 |
| SWP32/HSWP3 | N. bombycis | 37.4 | 951/316 | 7.29 | Yes/18 | 12/1/0 | Exospore | – | Wu et al. (2008); EF683103 |
| NbSWP7 | N. bombycis | 32.3 | 864/287 | 4.78 | Yes/19 | 7/0/1 | Exospore/endospore | – | Yang et al. (2015); EOB13707.1 |
| NbSWP9 | N. bombycis | 42.8 | 1104/367 | 8.32 | No | 7/0/3 | Exospore/endospore/polar tube | Transmembrane helix region | Yang et al. (2015, 2017); EOB13793.1 |
| NCER_100569 | N. ceranae | 20.4 | 552/183 | 4.37 | Yes/20 | 8/0/2 | – | – | Cornman et al. (2009) and Li et al. (2012); XM_002996306.1 |
| NCER_101082 | N. ceranae | 48.4 | 1281/426 | 8.37 | Yes/22 | 30/4/11 | – | – | Cornman et al. (2009) and Pelin et al. (2015); XM_002995858 or KKO74775 |
| SWP1 | Nosema pernyi | 32.0 | 837/278 | 7.27 | Yes/19 | 18/1/6 | – | – | KJ573111 |
| AlocSWP2 | Antonospora locustae | 25.0 | 669/222 | 5.16 | Yes/19 | 6/1/0 | Internal wall/external wall | HBM | KX255658 |