Table 2.
Patient data overview. N refers to number of cases. Seizure frequency was split in daily and weekly, unit of age (mean)—years and relative duration (mean) was normalized to age in %. Cognition was split in: n = normal, m = mild impairment, i = intermediate impairment, s = severe impairment. Location of resected tissue: c= central, f = frontal, h = hemispheric, o = occipital, p = parietal, t = temporal. * indicates missing data.
| Clinical data | ||||||||
|---|---|---|---|---|---|---|---|---|
| Type | n |
Sex (F:M) |
Age (±SD) |
Frequency d/w |
Duration (±SD) |
Mutations | Cognition | Location |
| Autopsy and biopsy | 15 | 8:7 | 13 (6,3) | – | – | – | 15n | 3f/4t/1o/1p* |
| TSC | 8 | 3:5 | 9 (7,1) | 5/3 | 78 (18) | 1TSC1/7TSC2 | 2n/2m/1i/3s | 5f/3t |
| MMCD | 6 | 1:5 | 11 (3,6) | 3/3 | 65 (21) | – | 2m/1i/3s | 3f/2t/1p |
| FCD IIA | 6 | 2:4 | 8 (4,9) | 3/3 | 65 (20) | – | 2n/3m* | 2f/1t/2o/1h |
| FCD IIB | 22 | 9:13 | 9 (11,8) | 11*/7* | 68 (18) |
1SMO/1NPRL3 1SUFU |
8n/3m/4i/2s * |
10f/3t/2o/6c/1p |
| Total | 57 | 23:34 | 10 (8,7) | 22/16 | 51 35 | – | – | 23f/13t/5o/6c/1h/3p |