Table 2.

Mean ± SD of Concentrations for 10 Normal Volunteers and 11 Patients with Cirrhotic Livers from a 28‐min 3D CSI Acquisition^a

Metabolite	Normal liver: Scan 1 / mmol/L wet tissue	Normal liver : Scan 2 / mmol/L wet tissue	Cirrhotic liver / mmol/L wet tissue	Difference between normal (scan 1) and cirrhotic livers/ %	P‐Value
α‐ATP	2.74 ± 0.11	2.69 ± 0.18	2.81 ± 0.11	2.3	0.10
Pi	2.23 ± 0.20	2.18 ± 0.18	1.96 ± 0.23	−12.2	0.005**
GPC	2.34 ± 0.46	2.35 ± 0.48	2.55 ± 0.59	9.1	0.18
GPE	1.50 ± 0.28	1.49 ± 0.21	1.82 ± 0.47	20.9	0.04*
PC	1.06 ± 0.16	0.99 ± 0.17	0.93 ± 0.24	−12.2	0.08
PE	0.77 ± 0.14	0.70 ± 0.11	0.76 ± 0.11	−1.47	0.42
PtdC/PEP	1.38 ± 0.31	1.35 ± 0.38	1.06 ± 0.32	−23.2	0.016*
NAD+	2.37 ± 0.14	2.33 ± 0.27	2.41 ± 0.38	1.7	0.38
UDPG	2.00 ± 0.22	2.06 ± 0.17	1.99 ± 0.37	−0.6	0.47
PDE	3.84 ± 0.68	3.84 ± 0.66	4.37 ± 0.92	13.7	0.08
PME	1.83 ± 0.27	1.69 ± 0.24	1.69 ± 0.28	−7.7	0.12

^aThe concentrations are based on a 2.65 mmol/L wet tissue γ‐ATP concentration. This assumption is reasonable for the normal volunteers, but does not necessarily hold for cirrhosis. The PDE concentration is the sum of the GPC and GPE concentrations, and the PME concentration is the sum of the PC and PE concentrations. Significant differences between healthy and cirrhotic concentrations are marked with stars: * P < 0.05, ** P < 0.01.