Table 1.

Clinicopathologic characteristics and association with overall pCR (n = 321)

Characteristic		All Patients(n = 321)	No pCR (n = 241)	pCR (n = 80)	p value
Age, years, median (range)		52 (28, 84)	52 (28, 81)	52 (28, 84)	0.94
Tumor size, cm, median (range)		6 (0.7,28)	6 (1, 28)	6.5 (0.7, 15)	0.55
Histology					0.23
	Ductal	276	74%	26%
	Lobular	22	91%	9%
	Mixed ductal/lobular	12	83%	17%
	Other*	11	64%	36%
cT¥					0.17
	T1	11	82%	18%
	T2	46	83%	17%
	T3	33	88%	12%
	T4	223	73%	27%
cN§					0.40
	N1	151	72%	28%
	N2	77	75%	25%
	N3	82	79%	21%
Receptor subtype					<0.001
	HR+/HER2−	138	93%	7%
	Triple negative	73	77%	23%
	HER2+	110	52%	48%

pCR, pathologic complete response; cT, clinical tumor stage; cN, clinical nodal stage; HR, hormone receptor

^*includes mammary (n = 4), mammary with lobular features (n = 3), metaplastic (n = 2), micropapillary (n = 2)

^¥excludes patients with occult cancer (Tx) at presentation (n = 8)

^§excludes patients who were cN0 at presentation (n = 11)