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. Author manuscript; available in PMC: 2017 Nov 21.
Published in final edited form as: Mol Pharm. 2017 Oct 25;14(11):3709–3717. doi: 10.1021/acs.molpharmaceut.7b00469

Figure 1.

Figure 1

Schematic of final two-compartment model that describes UA PK following both i.v. and oral doses. Vc is the central compartment; Vp is the peripheral compartment; CLd is intercompartmentral clearance between the central compartment and peripheral compartment; CL is the plasma clearance.