Table 2.
PK parameters | Description | Estimation |
---|---|---|
Vc (L/kg) | Volume of distribution in central compartment | 0.553 |
Vp (L/kg) | Volume of distribution in peripheral compartment | 2.27 |
CLt (L/h/kg) | Elimination clearance | 2.03 |
CLd (L/h/kg) | Intercompartment clearance | 0.607 |
Ka (h-1) | First-order absorption rate constant | 0.925 |
Alag (h) | absorption delay | 0.221 |
F (%) | Bioavailability | 8.18 |