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Final population pharmacokinetics parameters.
| PK parameters | Description | Estimation |
|---|---|---|
| Vc (L/kg) | Volume of distribution in central compartment | 0.553 |
| Vp (L/kg) | Volume of distribution in peripheral compartment | 2.27 |
| CLt (L/h/kg) | Elimination clearance | 2.03 |
| CLd (L/h/kg) | Intercompartment clearance | 0.607 |
| Ka (h-1) | First-order absorption rate constant | 0.925 |
| Alag (h) | absorption delay | 0.221 |
| F (%) | Bioavailability | 8.18 |
