Table 3. Potential of anti-CFP-10 and anti-ESAT-6 antibody/IFN-γ ratios to differentiate active and latent TB infection.

Biomarker	Cut-off	% Sensitivity (95% CI)	% Specificity (95% CI)	Youden's index (%)
Anti-CFP-10 antibody/IFN-γ ratio	512.0	48.5 (38.2–58.8)	89.7 (78.8–96.1)	38.1
Anti-ESAT-6 antibody/IFN-γ ratio	292.8	54.6 (44.2–64.8)	75.9 (62.8–86.1)	30.5