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. 2017 Oct 30;13(10):e1007068. doi: 10.1371/journal.pgen.1007068

Fig 3. EHC mutant embryo morphology.

Fig 3

A: Heterozygous littermate at E13.5. B: EHC mutant displays hydrocephalus in the mesencephalic vesicle (white arrow). C: Heterozygous littermate at E15.5. D: EHC mutant at E15.5 displays reduced hydrocephalus (arrow), although oedema in the spinal cord region is apparent (arrowhead). E: Heterozygous littermate at E17.5. F: EHC mutant has dome-shaped head (arrow), consistent with developmental defects arising from embryonic hydrocephalus. Scale bars: 1 mm. Abbreviations: MV: mesencephalic vesicle.