Table 4.
Relative mRNA expression of PCNA, 17β-HSD, P450c17 and AR in GD20 testes.
| group | n | 2−ΔΔCt
|
|||
|---|---|---|---|---|---|
| PCNA | 17β-HSD | P450c17 | AR | ||
| control | 10 | 1.64 ± 0.98 | 1.87 ± 0.26 | 1.53 ± 0.50 | 1.51 ± 0.43 |
| exposure | 10 | 0.87 ± 0.32* | 0.92 ± 0.26* | 0.92 ± 0.42* | 1.35 ± 0.56 |
Mother rats received oral gavage at 200 mg/kg from GD13 to GD18. Fetal gonadal organs (2 from 5 l in each treatment group) at GD20 were dissected for qPCR analysis. Data represent mean ± S.D.
: p < 0.05 compared to controls.