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. Author manuscript; available in PMC: 2017 Nov 29.
Published in final edited form as: Nat Immunol. 2017 May 29;18(7):744–752. doi: 10.1038/ni.3766

Figure 4. Ifih1R variant mice exhibit protection from EMCV challenge.

Figure 4

Male mice of indicated genotypes were injected intraperitoneally with 100 pfu of EMCV-K strain on day 0 and evaluated twice daily for clinical symptoms for 14 days. Mice were euthanized at a clinical score of 4. Graph displays combined data from three independent experiments with significance assessed using a Mantel-Cox test. Total numbers of animals: Ifih1NR/NR =11, Ifih1NR/R =10, Ifih1R/R =4. *p<0.05.

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