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A: Adipose DI, i.e., β-cell function relative to ATIS. B: Hyperbolic relationship between ATIS and first-phase insulin concentration during the hyperglycemic clamp. C: Glucose DI, i.e., β-cell function relative to peripheral IS. D: Hyperbolic relationship between peripheral IS and first-phase insulin concentration during the hyperglycemic clamp in youth with IGT vs. NGT.
