Table 2.

Hepatic and peripheral tissue IS of glucose metabolism in obese youth with IGT vs. NGT

	NGT (n = 97)	IGT (n = 41)	P
Fasting HGP (mg/kg/min)	2.3 ± 0.1	2.4 ± 0.1	NS
Hepatic IS (mg/kg/min ⋅ µU/mL)−1	16.0 ± 0.8	11.8 ± 1.0	0.001
Insulin-stimulated glucose disposal (mg/kg/min)	6.1 ± 0.2	4.7 ± 0.3	<0.0001
Insulin-stimulated glucose oxidation (mg/kg/min)	2.7 ± 0.1	2.3 ± 0.1	0.006
Insulin-stimulated nonoxidative glucose disposal (mg/kg/min)	3.3 ± 0.2	2.6 ± 0.3	0.028
Peripheral IS (mg/kg/min per µU/mL)	2.5 ± 0.2	1.7 ± 0.2	0.001

Values are reported as the mean ± SEM.