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. Author manuscript; available in PMC: 2017 Nov 21.
Published in final edited form as: Circulation. 2014 Oct 3;130(24):2152–2161. doi: 10.1161/CIRCULATIONAHA.114.010775

Table 1.

Resting Hemodynamics and Characteristics

Baseline 3 mo 6 mo 9 mo 12 mo P Value*
Body weight, kg 70±10 70±10 69±9 69±10 70±10 0.35
Lean body mass, kg 55.9±9.6 57.0±10.3 57.9±9.2 57.7±9.4 58.7±9.0 0.002
Plasma volume, L 2.87±0.40 2.97±0.57 3.01±0.47 3.08±0.49 3.10±0.61 0.003
Heart rate, bpm 67±6 66±6 68±8 66±9 60±5 0.004
SBP, mm Hg 113±6 113±8 107±4 109±8 116±7 0.001
DBP, mm Hg 67±6 63±7 61±3 66±9 68±6 0.0002
Cardiac output, L/min 6.5±1.1 7.1±1.1 7.6±1.2 7.5±1.5 6.7±1.1 0.0001
TPR, dyne·s·cm5 1033±180 917±167 820±146 838±173 1026±168 <0.0001

Results are presented as mean±SD. DBP indicates diastolic blood pressure; SBP, systolic blood pressure; and TPR, total peripheral resistance.

*

P value from repeated measures analysis time effect from baseline to 12 months.

Statistically significant difference compared with baseline from mixed model repeated measures analysis.

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