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. Author manuscript; available in PMC: 2018 Nov 21.
Published in final edited form as: Circulation. 2017 Oct 3;136(21):2037–2050. doi: 10.1161/CIRCULATIONAHA.117.028202

Figure 3. ECG analyses in control and HFpEF rats.

Figure 3

PR interval (A) and QRS width (B) in the two groups at 14 and 18 weeks show no differences between control and HFpEF rats. C. Representative ECGs showing QTc prolongation in HFpEF rat compared to control rat at 14 weeks. QTc prolongation in HFpEF rats is more pronounced at 18 weeks of age. D. QT interval was prolonged at 14 weeks of age with progression at 18 weeks of age. E. QTc was prolonged in HFpEF rats at 14 weeks compared to control rats and the prolongation is more pronounced at 18 weeks old. F. RR interval did not differ between the two groups. Control rats n=13 at 14 weeks and n=7 at 18 weeks. HFpEF rats n=31 at 14 weeks and n=5 at 18 weeks. Error line indicates mean and standard deviation. * denotes p < 0.05 and ** denotes p < 0.001. Mixed model regression with post-hoc testing (Tukey adjustment) was used for 3A-B and 3D-F.