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Comparison between human HFpEF and Dahl salt-sensitive rat model of HFpEF
| Human HFpEF | Rat HFpEF | |
|---|---|---|
| Hemodynamic abnormality | + | + |
| Echocardiographic diastolic dysfunction | + | + |
| QTc prolongation | + | + |
| High sudden death rate | + | + |
| Increased fibrosis | + | + |
| Elevated baseline heart rate | + | − |
| Co-morbidities | ||
| Hypertension | + | + |
| Diabetes Mellitus | + | − |
| Obesity | + | − |
| Old age | + | − |
