Figure 6. Validation of 12 epithelial differentiation genes in an independent study of mild, moderate and severe asthma (GSE41861).
Normalized expression values in each sample in GSE41861 (across different asthma severities) for the 12 epithelial differentiation “functional hub” genes identified in our network analysis. ****: p-value < 0.0001, ***: p-value < 0.001, **: p-value < 0.01, *: p-value < 0.05, n.s.: not significant, p-values between 0.05 and 0.15 noted on graphs; moderated Benjamini-Hochberg t-tests (with FDR significance adjustment).