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. Author manuscript; available in PMC: 2018 Nov 21.
Published in final edited form as: Anal Chem. 2017 Nov 3;89(22):12014–12022. doi: 10.1021/acs.analchem.7b02398

Figure 1.

Figure 1

The proposed microfluidic voltage-assisted liquid desorption electrospray ionization (VAL-DESI) source: (a) chip design, (b) a picture of the microfluidic chip prepared, and (c) a schematic illustrating the working principle of the source: the electrospray plume expends towards the “turned on” left sample channel (versus the “turned off” right sample channel) due to a potential difference of 3925V between the electrospray emitter and the sample channel outlet, hitting the sample solution and causing the analytes to desorb.