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. Author manuscript; available in PMC: 2018 Nov 15.
Published in final edited form as: Arch Biochem Biophys. 2017 Sep 27;634:38–46. doi: 10.1016/j.abb.2017.09.017

Table 1.

Characteristics of tension-pCa relationships in rat myocardium at 1.9 and 2.2µm SLs, for cTnI(WT), cTnI(1–167), and cTnI(1–193) fibers (Mean± SEM)

cTnI(WT)
cTnI(1–167)
cTnI(1–193)
1.9µm 2.2µm 1.9µm 2.2µm 1.9µm 2.2µm
Tmin (mN mm−2) 1.00±0.06 3.74±0.26* 1.24±0.19 3.34±0.09* 0.67±0.03 2.15±0.29*#
Tmax (mN mm−2) 13.25±1.75 31.25±0.62* 28.42±1.59 47.96±1.37* 13.38±1.07# 25.72±0.73*#
Tdev (mN mm−2) 12.25±1.50 27.51±0.54* 27.18±2.21 44.62±1.29* 12. 71±1.1# 23.5 7±0.69*#
pCa50 5.29±0.01 5.37±0.02* 5.44±0.01 5.46±0.02 5.39±0.01# 5.48±0.02*
nH 4.64±0.21 6.18±0.11* 8.15±0.39 7.27±0.21 4.68±0.15# 5.78±0.13*#
n fibers 6 6 7 7 6 6

Tmin, absolute tension value at pCa 8.0; Tmax, absolute tension value at pCa 4.8; Tdev, Ca2+-activated developed tension (Tmax- Tmin); pCa50 and nH represent fit parameters to a 3-parameter Hill equation.

*

Effect of SL for each truncation or wild-type; P <0.05

Truncation effect compared to cTnI(WT) at same SL; P <0.05

#

Difference between cTnI(1–193) and cTnI(1–167) at same SL; P <0.05