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. 2017 Nov 17;8:822. doi: 10.3389/fphys.2017.00822

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Copyright © 2017 Luo, Liu, Wu, Luo, Sun, Zheng, Hu, Pandol, Li, Han and Zeng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Altered biodiversity of gut microbiota in the new and recurrent tuberculosis patients in comparison with healthy control. (A,B) The new TB patients (NTB, n = 19), recurrent TB group (NTB, n = 18), and healthy human subjects, control (CG) are described in the Methods and Materials. The alpha-diversity, richness of gut microbes, was determined by ACE index and Chao1 index. (C,D) The ecological diversity of gut microbiota in the three groups of human subjects was measured by Simpson index and Shannon index. The p-values were calculated using Wilcox test. Statistical significance is displayed as ^*p < 0.05.