Table 1.

PFS and dosage by pazopanib combinations in the Pazo + study.

Drug combined with pazopanib	Number of patients	Median PFS	Dosage of experimental agent + dosage of pazopanib (# of pts)
Vorinostat	22	8.4 weeks	100 mg daily (n = 3)
			200 mg daily (n = 9)
			300 mg daily (n = 9)
			400 mg daily (n = 1)
Trametinib	13	13.7 weeks	2 mg + 800 mg daily (n = 10)
			2 mg + 600 mg daily (n = 2)
			1 mg + 800 mg daily (n = 1)
Everolimus	6	9.9 weeks	5 mg + 400 mg daily (n = 2)
			7.5 mg + 400 mg daily (n = 2)
			10 mg + 600 mg daily (n = 2)
Lapatinib	2	12.0 weeks	750 mg daily + 400 mg every other day (n = 2)
Trastuzumab	1	18.0 weeks	Loading dose 4 mg/kg followed by maintenance dose 2 mg/kg + 400 mg daily (n = 1)