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. 2016 Oct 25;21(6):961–970. doi: 10.1007/s10157-016-1340-2

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Receiver operator characteristic (ROC) curves for serum MZR concentration in once-a-day and 3-times-a-day administrations. The optimal cutoff level of C _max for CR was determined to be 1.1 μg/mL (sensitivity 0.625, specificity 1.000) in once-a-day administration (arrow)