Table 1.
Baseline characteristics and echocardiographic data
| All patients N = 148 |
PH (−) N = 83 |
PH (+) N = 65 |
P value | |
|---|---|---|---|---|
| Age, median (IQR) (years) | 82.0 (77.0–85.0) | 82.0 (77.0–85.0) | 82.0 (78.0–84.0) | 0.94 |
| Age ≥80 years, n (%) | 92 (62.2) | 49 (59.0) | 43 (66.2) | 0.38 |
| Men, n (%) | 56 (37.8) | 28 (33.7) | 28 (43.1) | 0.25 |
| Body mass index, median (IQR) (kg/m2) | 27.2 (25.2–30.6) | 27.2 (25.4–29.3) | 27.6 (25.3–31.5) | 0.42 |
| eGFR, median (IQR) (ml/min/1.73 m2) | 56.5 (40.0–72.0) | 54.5 (42.0–72.0) | 59.5 (37.0–72.0) | 0.86 |
| NYHA class, n (%) | 0.027 | |||
| I | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| II | 41 (27.7) | 28 (33.7) | 13 (20.0) | |
| III | 97 (65.5) | 47 (56.6) | 50 (76.9) | |
| IV | 10 (6.8) | 8 (9.6) | 2 (3.1) | |
| Arterial hypertension, n (%) | 139 (93.9) | 77 (92.8) | 62 (95.4) | 0.73 |
| Diabetes mellitus, n (%) | 48 (32.4) | 23 (27.7) | 25 (38.5) | 0.17 |
| Atrial fibrillation, n (%) | 52 (35.1) | 29 (34.9) | 23 (35.4) | 0.96 |
| Previous MI, n (%) | 48 (32.4) | 28 (33.7) | 20 (30.8) | 0.70 |
| Previous PCI, n (%) | 43 (29.1) | 21 (25.3) | 22 (33.8) | 0.26 |
| Previous CABG, n (%) | 28 (18.9) | 19 (22.9) | 9 (13.8) | 0.16 |
| CTO, n (%) | 14 (9.5) | 5 (6.0) | 9 (13.8) | 0.11 |
| Incomplete revascularization, n (%) | 22 (14.9) | 9 (10.8) | 13 (20.) | 0.12 |
| COPD, n (%) | 19 (12.8) | 8 (9.6) | 11 (16.9) | 0.19 |
| Stroke/TIA, n (%) | 17 (11.5) | 5 (6.0) | 12 (18.5) | 0.019 |
| Pacemaker, n (%) | 17 (11.5) | 8 (9.6) | 9 (13.8) | 0.43 |
| Logistic euroscore I, median (IQR) (%) | 14.5 (10.0–22.7) | 14.5 (10.0–22.0) | 14.5 (10.5–23.5) | 0.45 |
| STS, median (IQR) (%) | 6.2 (4.0–17.3) | 6.0 (4.0–14.8) | 7.3 (4.8–21.0) | 0.22 |
| TG max, median (IQR) (mmHg) | 86.0 (69.0–103.0) | 85.0 (66.5–97.0) | 88.0 (72.5–111.0) | 0.15 |
| TG mean, median (IQR) (mmHg) | 50.0 (42.0–63.0) | 49.0 (41.0–58.0) | 50.0 (44.5–65.5) | 0.14 |
| AVA, median (IQR) [cm2] | 0.7 (0.6–0.8) | 0.7 (0.6–0.8) | 0.6 (0.5–0.8) | 0.06 |
| LVEF, median (IQR) [%] | 60.0 (50.0–65.0) | 60.0 (48.0–65.0) | 60.0 (50.0–65.0) | 0.33 |
| AR before, n (%) | 0.70 | |||
| 0 | 48 (32.4) | 30 (36.1) | 18 (27.7) | |
| 1 | 75 (50.7) | 40 (48.2) | 35 (53.8) | |
| 2 | 20 (13.5) | 10 (12.0) | 10 (15.4) | |
| 3 | 5 (3.4) | 3 (3.6) | 2 (3.1) |
AR = aortic regurgitation; AVA = aortic valve area; CABG = coronary artery bypass graft; COPD = chronic obstructive pulmonary disease; CTO = chronic total occlusion; DM = diabetes mellitus; eGFR = estimated glomerular filtration rate; IQR = interquartile range; LVEF = left ventricle ejection fraction; MI = myocardial infarction; NYHA = New York Heart Association; PCI = percutaneous coronary intervention; sPAP = systolic pulmonary artery pressure; STS = The Society of Thoracic Surgeons; TG = transaortic gradient; TIA = transient ischemic attack