Fig. 1.

Software workflow for the calculation of 3D LV strain from 2D CMR cine imaging. Contours are applied to long axis cine images to construct endocardial and epicardial surface mesh models (a). A transmural hexahedral mesh is constructed (b), enabling the calculation of endocardial, epicardial and transmural strain from respective quadrangular components of each hexahedron. c Illustrates a 3D LV strain color map of endocardial principal strain and directions thereof at peak systole. d Provides global transmural strain curves for principal strain and conventional geometry-dependent directions