Table 2.
Biochemistry in control and study phase
| Control phase | Study phase | Treatment effect (95% CI) | p value | Carry-over p value |
Period effect p value |
|
|---|---|---|---|---|---|---|
| Serum creatinine (mg/dl) | 8.3 (7.2; 9.5) | 8.4 (7; 9.2) | 0 (−0.15 to 0.15) | 0.895 | 0.734 | 0.126 |
| Serum albumin (g/dl) | 3.8 (3.6; 4.0) | 4.0 (3.8; 4.2) | 0.2 (0.08 to 0.31) | <0.001 | 0.486 | 1 |
| Total cholesterol (mg/dl) | 155 (112.5; 183.3) | 171.5 (136.5; 198) | 21.32 (−6.5 to 45) | 0.132 | 0.181 | 1 |
| Triglycerides (mg/dl) | 213 (147.8; 276.8) | 242.5 (180; 290.5) | 21 (19.5 to 25) | <0.001 | 0.611 | 0.153 |
| Ferritin (ng/ml) | 289.5 (220.8; 333) | 275 (205.8; 299.5) | −15 (−48.5 to −4) | 0.003 | 0.865 | 0.94 |
| Serum phosphorus (mg/dl) | 4.3 (3.8; 5.3) | 4.4 (3.5; 5.0) | −0.10 (−0.45 to 0.33) | 0.678 | 0.376 | 0.624 |
| PTH (pg/ml) | 311.5 (224.3; 424.3) | 349.5 (241.8; 393.8) | 17.5 (−73.5 to 116) | 0.665 | 0.97 | 0.418 |
| Hb (gr/dl) | 11.3 (10.9; 11.8) | 11.9 (11.8; 12.1) | 0.65 (0.50 to 0.90) | <0.001 | 0.299 | 0.179 |
Numbers are median and 95% CI
CI confidence interval, PTH parathormone, Hb hemoglobin