Table 2.
Univariate and multivariate Cox proportional hazards analyses for 28-day all-cause mortality.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Group | ||||
| Normochloremia | Reference | Reference | ||
| Hypochloremia | 1.699 (1.129–2.557) | 0.011 | 1.484 (1.078–2.339) | 0.034 |
| Hyperchloremia | 1.762 (0.753–4.127) | 0.192 | 1.354 (0.564–3.250) | 0.497 |
| Age (per 1year increase) | 1.020 (1.003–1.037) | 0.023 | 1.017 (0.997–1.038) | 0.099 |
| Male (vs. Female) | 1.274 (0.840–1.932) | 0.255 | 1.147 (0.744–1.768) | 0.536 |
| MAP (per 1 mmHg increase) | 0.972 (0.956–0.988) | 0.001 | 0.982 (0.966–0.998) | 0.030 |
| SOFA score (per 1unit increase) | 1.220 (1.147–1.297) | <0.001 | 1.124 (1.047–1.206) | 0.001 |
| CVA (vs. non-CVA) | 1.797 (1.120–2.884) | 0.015 | 1.883 (1.129–3.139) | 0.015 |
| BUN (per 1 mg/dL increase) | 1.010 (1.008–1.013) | <0.001 | 1.004 (1.001–1.008) | 0.016 |
| Albumin (per 1 g/dL increase) | 0.369 (0.282–0.483) | <0.001 | 0.411 (0.302–0.559) | <0.001 |
| Lactate (per 1 mg/dL increase) | 1.163 (1.114–1.214) | <0.001 | 1.115 (1.057–1.175) | <0.001 |
Abbreviations; HR, hazard ratio; CI, confidence interval; MAP, mean arterial pressure; SOFA, sequential organ failure assessment; CVA, cerebrovascular accidents; BUN, blood urea nitrogen.